The Berger group studies the structure, mechanism and cellular assembly of eukaryotic multiprotein assemblies in transcription regulation and develops enabling technologies for DNA transfer, genome engineering and multigene expression in eukaryotic cells, tissues and organisms.
We are seeking up to two highly-skilled Research Technicians to actively participate in the ambitious research projects in our laboratory in the new Max Planck Centre for Minimal Biology at Bristol University. You will engage in designing and preparing multigene DNA constructs and utilize and further develop our award-winning MultiBac system for protein complex production and gene therapy applications. Outstanding applicants have a strong background in molecular biology and protein biochemistry. Experience in eukaryotic cell culture, baculovirus expression and/or a structural biology background is highly desirable.
Showing a high level of organization and independence, you will maintain the molecular biology and protein purification infrastructure including ordering of consumables and assist in operating the MultiBac platform in the eukaryotic expression facility. Moreover, you will archive and manage plasmid, baculovirus and protein stocks vital to the laboratory.
You will actively embrace the responsibility of managing technology platforms underpinning all research in the Berger lab.
Building stripped-down versions of life using protocells, genome delivery systems and synthetic cytoskeletons comprise some of the groundbreaking research due to take place at a new Centre launched at the University of Bristol on Wednesday 27 March. The Max Planck-Bristol Centre for Minimal Biology, a partnership between the University of Bristol and the Max Planck Society for the Advancement of Science (MPG) in Germany, aims to advance the future of health and medicine by understanding the fundamental nature of life.
Minimal biology is a new emerging field at the interface between the physical and life sciences. It aims to design and build artificial cells, minimal genomes, virus-like nanodevices and new cellular scaffolds, and seeks to understand the foundations of life and how it arose from non-living matter.
The partnership was solemnised by the signing of contracts by Professor Hugh Brady, Vice-Chancellor and President of the University of Bristol, and Professor Martin Stratmann, President of the Max Planck Society, at an inauguration event attended by around 100 delegates.